Thygeson's Superficial Punctate Keratitis

• Uncommon, non-contagious, primary corneal inflammation of unknown etiology.

Clinical Features

• Symptoms:
  • Patients usually present with bilateral keratitis
  • Characteristic remissions and exacerbations of tearing, foreign body sensation, and photophobia over several years.
• Signs:
  • Superficial coarse, punctate, discrete gray epithelial opacities which protrude into the tear film
  • More often located centrally
  • Usually remain for several weeks to several months and eventually fade
  • The conjunctiva is not involved.

Treatments

• Mild symptoms may be treated with simple lubricants.
• Low dose corticosteroids and topical cyclosporine are usually effective to reduce the duration of the recurrence.