Tezel Lab

Glaucoma, a multifactorial neurodegenerative disease, is a leading cause of blindness, with no curative treatment currently available. Tezel Lab evaluates the big picture of this complex disease that encompasses multiple stressors, multiple injury sites, multiple cell types, and multiple signaling pathways for asynchronous degeneration of RGCs during a chronic disease period. The longstanding interest of Tezel Lab in the cellular and molecular mechanisms, new treatment targets, and biomarkers of glaucoma motivates parallel studies that complement each other to better understand glaucomatous neurodegeneration and to provide a translational path toward new strategies for testing and treating glaucoma patients.