Anterior Lenticonus

Clinical Features

• Anterior conical protrusion of the central lens surface caused by the thinning of affected anterior capsule.
• Deficiency of the subjacent epithelium resulting in irregular astigmatism.
• The lens defect may be an isolated finding or more commonly associated with Alport's syndrome.
• Alport's syndrome is an autosomal recessive disorder with chronic progressive hemorrhagic nephropathy, bilateral high-tone perceptive deafness and ocular findings.
• Other ocular findings that have been described in Alport's syndrome are spherophakia, anterior polar and posterior cortical cataract, fundus lesions such as drusen, retinal flecks and retinal neovascularization.
• Spontaneous rupture of the capsule has also been reported.