Fleck

• Rare, autrosomal dominantly inherited.

Clinical Features

• Symptoms:
  • Often asymptomatic with no visual significant
  • May be associated with mild photophobia
  • Corneal erosions have been reported
• Signs:
  • Slowly progressive, diffuse, bilateral, irregularly shaped opacities in the posterior stroma of the cornea
  • The stromas in between lesions are typically clear
• Histopathology: abnormal keratocyte swelling with membrane-limited intracytoplasmic vacuoles containing complex lipids and glycosaminoglycans
• Treatment is not required.