Wang Lab

Selected Publications

  • Chang YH, Kang EY, Liu PK, Levi SR, Wang HH, Tseng YJ, Seo GH, Lee H, Yeh LK, Chen KJ, Wu WC, Lai CC, Liu L, Wang NK. 2022. Photoreceptor Manifestations of Primary Mitochondrial Optic Nerve Disorders. Invest Ophthalmol Vis Sci.  63(5):5. PubMed PMID: 35506936; PubMed Central PMCID: PMC9078049.
  • Kang EY, Liu PK, Wen YT, Quinn PMJ, Levi SR, Wang NK, Tsai RK. 2021. Role of Oxidative Stress in Ocular Diseases Associated with Retinal Ganglion Cells Degeneration. Antioxidants (Basel). 10(12). Review. PubMed PMID: 34943051; PubMed Central PMCID: PMC8750806.
  • Wang NK, Liu PK, Kong Y, Levi SR, Huang WC, Hsu CW, Wang HH, Chen N, Tseng YJ, Quinn PMJ, Tai MH, Lin CS, Tsang SH. 2021. Mouse Models of Achromatopsia in Addressing Temporal "Point of No Return" in Gene-Therapy. Int J Mol Sci. 22: 8069. PMID: 34360834; PMCID: PMC8347118
  • Peng WH, Liao ML, Huang WC, Liu PK, Levi SR, Tseng YJ, Lee CY, Yeh LK, Chen KJ, Chien CL, Wang NK. 2021. Conditional Deletion of Activating Rearranged During Transfection Receptor Tyrosine Kinase Leads to Impairment of Photoreceptor Ribbon Synapses and Disrupted Visual Function in Mice. Front Neurosci. 15:728905.  PubMed PMID: 34803580; PubMed Central PMCID: PMC8602685.
  • da Palma MM, Igelman AD, Ku C, Burr A, You JY, Place EM, Wang NK, Oh JK, Branham KE, Zhang X, Ahn J, Gorin MB, Lam BL, Ronquillo CC, Bernstein PS, Nagiel A, Huckfeldt R, Cabrera MT, Kelly JP, Bakall B, Iannaccone A, Hufnagel RB, Zein WM, Koenekoop RK, Birch DG, Yang P, Fahim AT, Pennesi ME. 2021. Characterization of the Spectrum of Ophthalmic Changes in Patients With Alagille Syndrome. Invest Ophthalmol Vis Sci. 62(7):27. PubMed PMID: 34185059; PubMed Central PMCID: PMC8254011.
  • Nassisi M, Smirnov VM, Solis Hernandez C, Mohand-Saïd S, Condroyer C, Antonio A, Kühlewein L, Kempf M, Kohl S, Wissinger B, Nasser F, Ragi SD, Wang NK, Sparrow JR, Greenstein VC, Michalakis S, Mahroo OA, Ba-Abbad R, Michaelides M, Webster AR, Degli Esposti S, Saffren B, Capasso J, Levin A, Hauswirth WW, Dhaenens CM, Defoort-Dhellemmes S, Tsang SH, Zrenner E, Sahel JA, Petersen-Jones SM, Zeitz C, Audo I. 2021. CNGB1-related rod-cone dystrophy: A mutation review and update. Hum Mutat. 42(6):641-666. PubMed PMID: 33847019; PubMed Central PMCID: PMC8218941.
  • Liu PK, Ryu J, Yeh LK, Chen KJ, Tsang SH, Liu L, Wang NK. 2021. A novel KCNV2 mutation in a patient taking hydroxychloroquine associated with cone dystrophy with supernormal rod response. Ophthalmic Genet. 42:458-463. PMID: 33960280
  • Liu CF, Chen SC, Chen KJ, Liu L, Chen YP, Kang EY, Liu PK, Yeung L, Wu WC, Lai CC, Lo FS, Wang NK. 2021. Higher HbA1c May Reduce Axial Length Elongation in Myopic Children: A Comparison Cohort Study. Acta Diabetol. 58:779-786. PMID: 33587176
  • Huang CY, Kang EY; Yeh LK; Wu AL; Liu PK; Huang IW; RyuJ; Liu L; Wu WC; Lai CC; Chen KJ; Wang NK. 2021. Predicting Visual Acuity in Bietti Crystalline Dystrophy: Evaluation of Image Parameters. BMC Ophthalmol. 21:68. PMID: 33541298; PMCID: PMC7860191
  • Zhang L, Cui X, Han Y, Park KS, Gao X, Zhang X, Yuan Z, Hu Y, Hsu CW, Li X, Bassuk AG, Mahajan VB, Wang NK, Tsang SH. 2019. Hypoxic drive caused type 3 neovascularization in a preclinical model of exudative age-related macular degeneration. Hum Mol Genet. 28:3475-3485. PMID: 31518400; PMCID: PMC7275777
  • Wang NK, Mahajan VB, Tsang SH. 2019. Therapeutic Window for Phosphodiesterase 6-Related Retinitis Pigmentosa. JAMA Ophthalmol. 137(6):679-680. PMID: 30998807
  • Kang EY, Lo FS, Wang JP, Yeh LK, Wu AL, Tseng YJ, Yeh CT, Liu L, Chen KJ, Wu WC, Lai CC, Wang NK; Chang Gung Juvenile Diabetes Eye Study Group. 2018. Nomogram for prediction of non-proliferative diabetic retinopathy in juvenile-onset type 1 diabetes: a cohort study in an Asian population. Sci Rep. 8:12164. PMID: 30111889; PMCID: PMC6093915
  • Lin YH, Wang NK, Yeung L, Lai CC, Chuang LH. 2018. Juvenile open-angle Glaucoma associated with Leber's hereditary optic neuropathy: a case report and literature review. BMC Ophthalmol. 18(1):323. PMID: 30558558; PMCID: PMC6296145
  • Wu AL, Wang JP, Tseng YJ, Liu L, Kang YC, Chen KJ, Chao AN, Yeh LK, Chen TL, Hwang YS, Wu WC, Lai CC, Wang NK. 2018. Multimodal Imaging of Mosaic Retinopathy in Carriers of Hereditary X-linked Recessive Diseases. Retina. 38(5):1047-1057. PMID: 28376043
  • Wang NK, Fu Y, Wang JP, Kang EY, Wu AL, Tseng YJ, Yeh LK, Chen KJ, Wu WC, Ho WJ, Lai CC. 2017. Peripheral Vascular Endothelial Dysfunction in Central Serous Chorioretinopathy. Invest Ophthalmol Vis Sci. 58(11):4524-4529. PMID: 28877318
  • Wang NK, Lai CC, Wang JP, Wu WC, Liu L, Yeh LK, Tseng HJ, Chang CJ, Lo FS; Chang Gung Juvenile Diabetes Eye Study Group. 2016. Risk factors associated with the development of retinopathy 10 yr after the diagnosis of juvenile-onset type 1 diabetes in Taiwan: a cohort study from the CGJDES. Pediatr Diabetes. 17(6):407-16. PMID: 26332951
  • Wang NK, Wu YM, Wang JP, Liu L, Yeung L, Chen YP, Chen YH, Yeh LK, Wu WC, Chuang LH, Lai CC. 2016. Clinical Characteristics of Posterior Staphylomas in Myopic Eyes with Axial Length Shorter than 26.5 mm. Am J Ophthalmol. 162:180-190.e1. PMID: 26585213
  • Wang NK, Liu L, Chen HM, Tsai Shawn, Chang TC, Tsai TH, Yang CM, Chao AN, Chen KJ, Kao LY, Yeung L, Yeh LK, Hwang YS, Wu WC, Lai CC. 2015. Clinical Presentations of X-Linked Retinoschisis in Taiwanese Patients Confirmed by Genetic Sequencing. Molecular Vision: 21:487-501. PMID: 25999676; PMCID: PMC4415592
  • Wu WC, Lien R, Liao PJ, Wang NK, Chen YP, Chao AN, Chen KJ, Chen TL, Hwang YS, Lai CC. Serum Levels of Vascular Endothelial Growth Factor and Related Factors After Intravitreous Bevacizumab Injection for Retinopathy of Prematurity. JAMA Ophthalmol. 2015 Apr;133(4):391-7. doi: 10.1001/jamaophthalmol.2014.5373. PubMed PMID: 25569026.
  • Lai CC, Chen YP, Wang NK, Chuang LH, Liu L, Chen KJ, Hwang YS, Wu WC, Chen TL. 2015. Vitrectomy with Internal Limiting Membrane Repositioning and Autologous Blood for Macular Hole Retinal Detachment in Highly Myopic Eyes. Ophthalmology. 122(9):1889-98. PMID: 26143541
  • Liu CF, Liu L, Lai CC, Chou CL, Yeh LK, Chen KJ, Chen YP, Wu WC, Chuang LH, Sun CC, Wang NK. 2014. Multimodal Imaging Including Spectral Domain Optical Coherence Tomography and Confocal Near Infrared Reflectance for Characterization of Lacquer Cracks in Highly Myopic Eyes. Eye (Lond). 28(12):1437-45. PMID: 25233819; PMCID: PMC4268461
  • Wang NK, Lai CC, Liu CH, Yeh LK, Chou CL, Kong J, Nagasaki T, Tsang SH, Chien CL. 2013. Origin of fundus hyperautofluorescent (AF) spots, and their role in retinal degeneration in a Mouse Model of Goldmann-Favre Syndrome. Dis Model Mech. 6(5):1113-22. PMID: 23828046; PMCID: PMC3759331
  • Rao X, Wang NK, Chen YP, Hwang YS, Chuang LH, Liu IC, Chen KJ, Wu WC, Lai CC. 2013. Outcomes of Outpatient Fluid-Gas Exchange for Open Macular Hole After Vitrectomy. Am J Ophthalmol. 156(2):326-333.e1. PMID: 23688710
  • Wang NK, Lai CC, Chou CL, Chen YP, Chuang LH, Chao AN, Tseng HJ, Chang CJ, Wu WC, Chen KJ, Tsang SH. 2013. Choroidal Thickness and Biometric Markers for the Screening of Lacquer Cracks in Patients with High Myopia. PLoS One. 8(1):e53660. PMID: 23349728; PMCID: PMC3551908
  • Wang NK, Chuang LH, Lai CC, Chou CL, Chu HY, Yeung L, Chen YP, Chen KJ, Wu WC, Chen TL, Chao AN, Hwang YH. 2012. Multimodal Fundus Imaging in Fundus Albipunctatus with RDH5 Mutation: A Newly Identified Compound Heterozygous Mutation and Review of the Literature. Doc Ophthal. 125(1):51-62. PMID: 22669287
  • Wu WC, Lin RI, Shih CP, Wang NK, Chen YP, Chao AN, Chen KJ, Chen TL, Hwang YS, Lai CC, Huang CY, Tsai S. 2012. Visual Acuity, Optical Components, and Macular Abnormalities in Patients with a History of Retinopathy of Prematurity. Ophthalmology. 119(9):1907-16. PMID: 22578258
  • Wang NK, Lai CC, Chu HY, Chen YP, Chen KJ, Wu WC, Yeh LK, Chuang LH, Chen TL. 2012. Classification of Early Dry-Type Myopic Maculopathy with Macular Choroidal Thickness. Am J Ophthalmol. 153(4):669-677.e2. PMID: 22071232
  • Tosi J, Davis RJ, Wang NK, Naumann M, Lin CS, Tsang SH. 2011. shRNA knockdown of guanylate cyclase 2e or cyclic nucleotide gated channel alpha 1 increases photoreceptor survival in a cGMP phosphodiesterase mouse model of retinitis pigmentosa. J Cell Mol Med. 15(8):1778-87. PMID: 20950332; PMCID: PMC3071858
  • Tosi J#, Wang NK#, Zhao J, Chou CL, Kasanuki JM, Tsang SH, Nagasaki T. 2010. Rapid and Noninvasive Imaging of Retinal Ganglion Cells in Live Mouse Models of Glaucoma. Mol Imaging Biol 12(4):386-93. (#Co- first Author) PMID: 19937134; PMCID: PMC2889038
  • Wang NK, Tosi J, Kasanuki JM, Chou CL, Kong J, Parmalee N, Wert KJ, Allikmets R, Lai CC, Chien CL, Nagasaki T, Lin CS, Tsang SH. 2010. Transplantation of Reprogrammed Embryonic Stem Cells Improves Visual Function in a Mouse Model for Retinitis Pigmentosa. Transplantation. 89(8):911-9. PMID: 20164818; PMCID: PMC2855750
  • Braunstein A, Trief D, Wang NK, Chang S, Tsang SH. 2010. Vitamin A deficiency in New York City. Lancet. 376(9737):267. PMID: 20663549; PMCID: PMC2929009
  • Wang NK, Fine HF, Chang S, Chou CL, Cella W, Tosi J, Lin CS, Nagasaki T, Tsang SH. 2009. Cellular Origin of Fundus Autofluorescence in Patients and Mice with Defective NR2E3 Gene. Br J Ophthalmol. 93(9):1234-40. PMID: 19429590; PMCID: PMC2742679
  • Wang NK, Chen TL, Lai CC, KuoYH, ChaoAN, Wu WC, Chen KJ, Hwang YS, Chen YP, Liu L. 2009. Clinical Characteristics and Surgical Outcomes of Paediatric Retinal Detachment with Lens Disorders. J Pediatr Ophthalmol Strabismus 46:160-167 PMID: 19496497
  • Tosi J, Janisch KM, Wang NK, Kasanuki JM, Flynn JT, Lin CS, Tsang SH. 2009. Cellular and Molecular Origin of Circumpapillary Dysgenesis of the Pigment Epithelium. Ophthalmology. 116(5):971-80. PMID: 19410955; PMCID: PMC2717946
  • Wang NK, Chen YP, Lai CC, Chen TL, Yang KJ, Kuo YH, Chao AN, Wu WC, Chen KJ, Hwang YS, Yeung L, Liu L. 2009. Pediatric Retinal Detachment: Comparison of High Myopia and Extreme Myopia. Br J Ophthalmol 93(5):650-5. PMID: 19098036
  • Lima LH, Cella W, Greenstein VC, Wang NK, Busuioc M, Smith RT, Yannuzzi LA, Tsang SH. 2009. Structural Assessment of Hyperautofluorescent Ring in Patients with Retinitis Pigmentosa. Retina 29 (7):1025-1031. PMID: 19584660; PMCID: PMC2749567
  • Davis R, Tosi J, Janisch K, Kasanuki J, Wang NK, Kong J, Tsui I, Cilluffo M, Woodruff M, Fain GL, Lin CS, Tsang S. 2008. Functional rescue of degenerating photoreceptors in mice homozygous for a hypomorphic cGMP phosphodiesterase 6 allele (Pde6bH620Q). Invest Ophthalmol Vis Sci: 49(11):5067-76. PMID: 18658088; PMCID: PMC2715364
  • Wang NK, Chen YP, Yeung L, Chen KJ, Chao AN, Kuo YH, Lee JS, Lai CC. 2007. Traumatic Pediatric Retinal Detachment Following Open Globe Injury. Ophthalmologica 221(4):255-263. PMID: 17579292
  • Wang NK, Tsai CH, Chen YP, Yeung L, Wu WC, Chen TL, Lin KK, Lai CC. 2005. Pediatric Rhegmatogenous Retinal Detachment in East Asians. Ophthalmology 112(11):1890-1895.  PMID: 16271317

Complete List of Publications