Cotton-wool Spots
Clinical Features
- Symptoms:
- Asymptomatic
- Various degree of blurry vision
- Signs:
- Localized, white-yellowish, fluffy areas of nerve fiber layer edema
- Focal ischemia that causes axoplasmic flow interruption, results in drainage of axoplasmic content into the retina
- Commonly found in many vascular diseases:
- AIDS
- Diabetic retinopathy
- Hypertensive retinopathy
- Collagen vascular diseases such as SLE, dermatomyositis and polyarteritis nodosa