Rao Lab

Selected Publications

Image of DNA forming into a tree with leaves and roots

Early Detection of Motor Markers

Gait and Balance Impairments in Huntington Disease

  • Rao, A.K., Muratori, L., Louis, E.D., Moskowitz, C.B. and Marder, K.S. Spectrum of gait impairments in Presymptomatic and symptomatic Huntington’s disease. Movement Disorders, 2008, Vol 23 (8): pp. 1100-1107. PMID: 18412252
  • Rao, A.K., Muratori, L., Louis, E.D., Moskowitz, C.B. and Marder, K.S. Clinical measurement of mobility and balance impairments in Huntington’s disease: Validity and responsiveness. Gait & Posture: 2009, 29: 433-436. PMID: 19111470.
  • Rao, A.K., Louis, E.D. and Marder, K.S. Clinical assessment of mobility and balance impairments in pre-symptomatic Huntington’s disease. Gait and Posture: 2009, 30: 391-393. PMID: 19647432.
  • Rao AK, Mazzoni PM, Wasserman P and Marder KS. Longitudinal Change in Gait and Motor Function in Pre-manifest Huntington’s Disease. PLoS Curr. 2011 Oct 4;3:RRN1268. PMID: 22008726 PMCID: PMC31932

Aging-Related Decrements in Gait, Balance, and Physical Activity

  • Porciuncula F, Rao AK, McIsaac T. Aging-related decrements during specific phases of the dual-task Timed Up-and-Go test. Aging Clinical and Experimental Research. 2016 Feb;28(1):121-30. [Epub ahead of print] PubMed PMID: 25995166.
  • Osoba MY, Rao AK, Agrawal SK, Lalwani AK. Balance and gait in the elderly: A contemporary review. Laryngoscope Investig Otolaryngol. 2019 Feb 4;4(1):143-153. doi: 10.1002/lio2.252. eCollection 2019 Feb. Review. PubMed PMID: 30828632; PubMed Central PMCID: PMC6383322.
  • Rao AK. Wearable sensor technology to measure physical activity (PA) in the elderly. Current Geriatrics Reports. 2019. 8: 55. https://doi.org/10.1007/s13670-019-0275-3
  • Zhang H, Yin Y, Chen Z, Zhang Y, Rao AK, Guo Y, Zanotto D. Wearable Biofeedback System to Induce Desired Walking Speed in Overground Gait Training. Sensors. 2020. Jul 18;20(14):4002.doi: 10.3390/s20144002. PMID: 32708450. PMCID: PMC7412458
  • Zhao, Q., Chen, Z., Landis, C., Lytle, A., Rao, A.K., Zanotto, D., & Guo, Y. Gait monitoring for older adults during guided walking: An integrated assistive robot and wearable sensor approach. Wearable Technologies. 2022;3, E28. doi:10.1017/wtc.2022.23.

Gait and Balance Impairments in Essential Tremor and Parkinson’s Disease

  • Rao AK and Louis ED. Ataxic gait in Essential Tremor: A disease-associated figure? Tremor and Other Hyperkinetic Movements. 2019. 2019;9. doi: 10.7916/d8-28jq-8t52. eCollection 2019. Review. PubMed PMID: 31413894; PubMed Central PMCID: PMC6691745.
  • Rao, A.K. Gillman, A, and Louis, E.D. Quantitative gait analysis in essential tremor reveals impairments that are maintained into advanced age. Gait and Posture. 2011, 34: 65-70. PMID: 21478017 PMCID: PMC3575132.
  • Rao AK, Uddin J, Gillman A, Louis ED. Cognitive motor interference during dual-task gait in Essential Tremor. Gait and Posture. 2013. 38: 403–409. PMID: 23369662 PMCID: PMC3679258.
  • Louis ED and Rao AK. Functional Aspects of Gait in Essential Tremor: A Comparison with Age-Matched Parkinson’s Disease Cases, Dystonia Cases, and Controls. Tremor and Other Hyperkinetic Movements. 2015 May 27;5. pii: tre-5-308. doi: 10.7916/D8B27T7J. PubMed PMID: 26056611; PubMed Central PMCID: PMC4454999.

Mechanisms Underlying Motor Impairments

  • Rao, A.K., Marder, K.S. and Gordon, A.M Coordination of fingertip forces during precision grip in premanifest Huntington’s disease. Movement Disorders. 2011, 26(5): 862-869. PMID: 21394785 PMCID: PMC3116202.
  • Rao AK, Marder KS, Uddin J, Rakitin BC. Variability in interval production is due to timing dependent deficits in Huntington’s disease. Movement Disorders.  2014. 29(12): 1516-1522. PMID: 25154339. PMCID: PMC4188696.
  • Porciuncula F, Wasserman P, Marder KS, Rao AK. Quantifying postural control in premanifest and manifest Huntington’s Disease using wearable sensors. Neurorehabilitation and Neural Repair. 2020. Vol. 34(9) 771–783. doi: 10.1177/1545968320939560. PMID: 32672492

Design and Test Exercise Interventions in Huntington Disease

  • Fritz N, Kegelmeyer D, Rao AK, Quinn L, Nance M, Kloos A. Coordination of Care Among Physical Therapists and Neurologists in Huntington’s Disease. Neurology Clinical Practice. 2022. In Press.
  • Quinn L, Kegelmeyer D, Kloos A, Rao AK, Busse M, Fritz NE. Clinical recommendations to guide physical therapy practice for Huntington disease. Neurology. 2020 Feb 4;94(5):217-228. doi: 10.1212/WNL.0000000000008887. Epub 2020 Jan 6. Review. PubMed PMID: 31907286; PubMed Central PMCID: PMC7080285.
  • Fritz NE, Rao AK, Kegelmeyer D, Kloos A, Busse M, Hartel L, Carrier J, Quinn L. Physical Therapy and Exercise Interventions in Huntington's Disease: A Mixed Methods Systematic Review. J Huntingtons Dis. 2017;6(3):217-235. doi: 10.3233/JHD-170260. PubMed PMID: 28968244.
  • Moskowitz CB, Rao AK. Making a measurable difference in advanced Huntington disease care. Handb Clin Neurol. 2017;144:183-196. doi:10.1016/B978-0-12-801893-4.00016-X. PubMed PMID: 28947117.
  • Rao AK. Measuring function in chronic progressive disorders. American Journal of Occupational Therapy. 2013. 67(5): 499-501. PMID: 23968786.

Chapters, Monographs, and Editorials

  • Rao, A.K. Gait Disorders. In Merritt's Neurology. Fourteenth Edition. ED Louis, S Mayer & JM Noble (Eds.). Philadelphia, PA. Volters-Kluwer. 2022, pp. 122-131.
  • Rao AK and Shah H. Gait failure. In R. Marshall and S. Mayer (Eds.). On Call Neurology. 4th Edition. 2021. In Press. Elsevier. St. Louis, MO. Pp. 161-172.
  • Rao AK Approaches to motor control dysfunction in stroke: An evidence-based review. In G. Gillen (Ed.), Stroke Rehabilitation: A function-based approach. Fifth Edition. Elsevier. St. Louis, MO. 2021, pp. 332-348.

Full Publications List