Overview
Current research is focussed on Barrett's esophagus. Targeted biopsies using confocal endomicroscopy for more accurate diagnosis. Radiofrequency ablation of Barrett's esophagus. Endoscopic mucosal resection of pre-cancerous lesions and early cancer. Blood tests and biopsy tests for early detection of esophageal cancer. Prevention of esophageal cancer in Barrett's esophagus.
Areas of Expertise / Conditions Treated
- Barrett's Esophagus
- Cancer Prevention
- Capsule Endoscopy
- Esophageal Disease
- Esophagus Disorder
- Gastrointestinal (GI) Endoscopy Procedures
- Gastrointestinal Cancer
- Gastrointestinal Disorder
- Pancreatic Cancer
- Second Opinion
- Swallowing Disorder
Academic Appointments
- Professor of Medicine at CUMC
Hospital Affiliations
- NewYork-Presbyterian / Columbia University Irving Medical Center
Gender
- Male
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Credentials & Experience
Education & Training
- Columbia University College of Physicians and Surgeons
- Internship: Yale-New Haven Hospital
- Residency: New York Hospital - Cornell Medical Center
- Residency: Yale-New Haven Hospital
- Fellowship: New York Hospital - Cornell Medical Center
Board Certifications
- Gastroenterology
- Internal Medicine
Research
I am a trained gastroenterologist with clinical expertise in the areas of pancreatic cancer, Barrett’s esophagus, and other related diseases. My specialties include digestive and liver disorders, gastroenterology, and cancer. I have authored over 130 scientific articles in peer-reviewed journals, 290 reviews, editorials, and book chapters. I have served on two consecutive 4-year terms as Editorin-Chief of Gastrointestinal Endoscopy, the official journal of the ASGE. Identifying ways to prevent upper-GI cancers is the main goal of my research. My research areas include studying Barrett's esophagus; targeted biopsies using confocal endomicroscopy for more accurate diagnosis; radiofrequency ablation of Barrett's esophagus; endoscopic mucosal resection of pre-cancerous lesions and early cancer. I have also worked extensively on developing blood and biopsy tests for early detection and prevention of esophageal cancers; and the use of endoscopic ultrasound for diagnosis and staging of gastrointestinal cancers.
Selected Publications
- Lightdale CJ. Gastroesophageal Reflux Disease: Changing the Conversation. Gastrointest Endosc Clin N Am. 2020 Apr;30(2):xi-xii. doi: 10.1016/j.giec.2020.02.001. PMID: 32146952
- Ginès A, Lightdale CJ. How I do a diagnostic EUS. Endoscopy. 2019; 51(10):973-975. PMID: 31307101
- Goldblum JR, Shaheen NJ, Vennalaganti PR, Sharma P, Lightdale CJ. WATS for Barrett's surveillance. Gastrointest Endosc. 2018 Jul;88(1):201-202. PMID: 29935618