Baldwin Lab

Dr. Baldwin’s laboratory aims to improve critical illness survivorship and spans four areas of study.

1. We conduct epi-translational research to endophenotype acute respiratory failure survivors and elucidate the mechanisms post-ICU frailty as therapeutic targets for improving physical recovery. We have identified frailty subtypes in acute respiratory failure survivors, and discovered that aging-related plasma biomarkers of inflammation, neuro-endocrinopathy, and muscle mitochondrial myopathy are potential therapeutic targets for post-ICU interventions.
2. We conduct reverse translational research focused on the development of airway administered cellular therapeutics to attenuate and resolve inflammation in ARDS.
3. We conduct clinical and epidemiologic research with a focus on clinical risk prediction modeling and health disparities outcomes.
4. We conduct research related to palliative care that aims to improve ICU survivorship. We developed novel palliative care interventions for mechanical ventilation patients, such as chaplain-led communication-board-guided spiritual care.